Journal article
Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis
Abstract
Preclinical and clinical evidence suggests that mesenchymal stem cells (MSCs) may be beneficial in treating both acute myocardial infarction (AMI) and ischemic heart failure (IHF). However, the safety profile and efficacy of MSC therapy is not well-known. We conducted a systematic review of clinical trials that evaluated the safety or efficacy of MSCs for AMI or IHF. Embase, PubMed/Medline, and Cochrane Central Register of Controlled Trials …
Authors
Lalu MM; Mazzarello S; Zlepnig J; Dong YY; Montroy J; McIntyre L; Devereaux PJ; Stewart DJ; Mazer CD; Barron CC
Journal
Stem Cells Translational Medicine, Vol. 7, No. 12, pp. 857–866
Publisher
Oxford University Press (OUP)
Publication Date
December 1, 2018
DOI
10.1002/sctm.18-0120
ISSN
2157-6564