Journal article
Impact of Vertebral Fractures and Glucocorticoid Exposure on Height Deficits in Children During Treatment of Leukemia
Abstract
Objective: To assess the effect of vertebral fractures (VF) and glucocorticoid (GC) exposure on height deficits in children during treatment of acute lymphoblastic leukemia (ALL).
Methods: Children with ALL treated without cranial radiation therapy (n = 160; median age, 5.1 years; 58.1% male) were followed prospectively for 6 years. Spinal deformity index (SDI) was used to quantify VF status.
Authors
Ma J; Siminoski K; Alos N; Halton J; Ho J; Cummings EA; Shenouda N; Matzinger MA; Lentle B; Jaremko JL
Journal
The Journal of Clinical Endocrinology & Metabolism, Vol. 104, No. 2, pp. 213–222
Publisher
The Endocrine Society
Publication Date
February 1, 2019
DOI
10.1210/jc.2018-01083
ISSN
0021-972X