Journal article
Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy
Abstract
We have developed novel instrumentation using confocal and widefield microscopy to image and analyze thrombus formation in real time in the microcirculation of a living mouse. This system provides high-speed, near-simultaneous acquisition of images of multiple fluorescent probes and a brightfield channel, and supports laser-induced injury through the microscope optics. Although this imaging facility requires interface of multiple hardware …
Authors
Celi A; Merrill-Skoloff G; Gross P; Falati S; Sim DS; Flaumenhaft R; Furie BC; Furie B
Journal
Journal of Thrombosis and Haemostasis, Vol. 1, No. 1, pp. 60–68
Publisher
Elsevier
Publication Date
1 2003
DOI
10.1046/j.1538-7836.2003.t01-1-00033.x
ISSN
1538-7933