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Randomized controlled trial of misoprostol for...
Journal article

Randomized controlled trial of misoprostol for second-trimester pregnancy termination associated with fetal malformation

Abstract

OBJECTIVE: Our purpose was to compare the effectiveness, women's views of the termination procedure, and success of umbilical cord culture for vaginal and oral misoprostol versus intra-amniotic prostaglandin PGF(2alpha) for second-trimester pregnancy termination (STPT). STUDY DESIGN: We randomized 217 women, 15 to 24 weeks' gestation, into 3 groups. Oral (OM) and vaginal (VM) misoprostol groups received 400 microg of misoprostol every 4 hours …

Authors

Akoury HA; Hannah ME; Chitayat D; Thomas M; Winsor E; Ferris LE; Einarson TR; Seaward PGR; Ryan G; Willan AR

Journal

American Journal of Obstetrics and Gynecology, Vol. 190, No. 3, pp. 755–762

Publisher

Elsevier

Publication Date

March 2004

DOI

10.1016/j.ajog.2003.09.037

ISSN

0002-9378