In vivo regional cerebral blood volume: quantitative assessment with 3D T1-weighted pre- and postcontrast MR imaging.

PURPOSE: To assess the use of pre-and postcontrast three-dimensional (3D) T1-weighted images to obtain quantitative regional cerebral blood volume (rCBV) maps and to delineate the vascular system of the brain. MATERIALS AND METHODS: Sagittal 3D pre-and postcontrast T1-weighted images were acquired in 10 patients and two volunteers. The images were processed with a knowledge-based segmentation algorithm to obtain independent blood volume maps of …