Journal article
NLRP3 deficiency exacerbates enterovirus infection in mice
Abstract
The role for the NOD-like receptor (NLR) P3 inflammasome in enterovirus infection remains controversial. Available data suggest that the NLRP3 inflammasome is protective against enterovirus A71 but detrimental to the host during coxsackievirus B3 (CVB3) infection. CVB3 is a common etiologic agent associated with myocarditis and pancreatitis. Previous findings on the role of NLRP3 in CVB3 were based primarily on indirect evidence. Here, we …
Authors
Wang C; Fung G; Deng H; Jagdeo J; Mohamud Y; Xue YC; Jan E; Hirota JA; Luo H
Journal
The FASEB Journal, Vol. 33, No. 1, pp. 942–952
Publisher
Wiley
Publication Date
1 2019
DOI
10.1096/fj.201800301rrr
ISSN
0892-6638