Aqueous electrophoretic deposition of drugs using bile acids as solubilizing, charging and film-forming agents

A new electrophoretic deposition (EPD) technique is reported for the fabrication of composite coatings containing drugs, which have low solubility in water. We present a conceptually new approach, which is based on the use of bile salts (BS) as solubilizing, charging and film forming agents. Composite films are obtained using tetracycline and ibuprofen as model drugs with commercial BS, such as cholic acid sodium salt and deoxycholic acid …