Journal article
Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001
Abstract
Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 05-001 tested a new risk stratification system in children and adolescents with newly diagnosed acute lymphoblastic leukemia (ALL). At study entry, B-ALL patients were classified as standard risk (SR) or high risk (HR) based on age, white blood cell (WBC) count, and central nervous system status. After achieving complete remission (CR), patients with high end-induction minimal residual …
Authors
Vrooman LM; Blonquist TM; Harris MH; Stevenson KE; Place AE; Hunt SK; O'Brien JE; Asselin BL; Athale UH; Clavell LA
Journal
Blood Advances, Vol. 2, No. 12, pp. 1449–1458
Publisher
American Society of Hematology
Publication Date
June 26, 2018
DOI
10.1182/bloodadvances.2018016584
ISSN
2473-9529
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAge FactorsChildChild, PreschoolClinical Trials, Phase III as TopicFemaleHistone-Lysine N-MethyltransferaseHumansIkaros Transcription FactorInfantLeukocyte CountMaleMulticenter Studies as TopicMultivariate AnalysisMyeloid-Lymphoid Leukemia ProteinNeoplasm, ResidualPrecursor B-Cell Lymphoblastic Leukemia-LymphomaRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsSurvival Analysis