Journal article
Atypical antipsychotic drugs and the risk for acute kidney injury and other adverse outcomes in older adults: a population-based cohort study.
Abstract
BACKGROUND: Several adverse outcomes attributed to atypical antipsychotic drugs, specifically quetiapine, risperidone, and olanzapine, are known to cause acute kidney injury (AKI). Such outcomes include hypotension, acute urinary retention, and the neuroleptic malignant syndrome or rhabdomyolysis.
OBJECTIVE: To investigate the risk for AKI and other adverse outcomes associated with use of atypical antipsychotic drugs versus nonuse.
Authors
Hwang YJ; Dixon SN; Reiss JP; Wald R; Parikh CR; Gandhi S; Shariff SZ; Pannu N; Nash DM; Rehman F
Journal
Annals of Internal Medicine, Vol. 161, No. 4, pp. 242–248
Publisher
American College of Physicians
Publication Date
August 19, 2014
DOI
10.7326/m13-2796
ISSN
1056-8751