Journal article
Higher dose versus lower dose of antiviral therapy in the treatment of herpes zoster infection in the elderly: a matched retrospective population-based cohort study
Abstract
BackgroundHigher versus lower doses of antiviral drugs used to treat herpes zoster infection may lead to more adverse drug events in older adults, particularly those with chronic kidney disease.MethodsWe conducted a matched retrospective population-based cohort study of older adults (mean 77 years) in Ontario, Canada who initiated in the outpatient setting a higher (n = 23,256) or lower (n = 3,876) dose of one of three oral antivirals for the …
Authors
Lam NN; Fleet JL; McArthur E; Blake PG; Garg AX
Journal
BMC Pharmacology and Toxicology, Vol. 15, No. 1,
Publisher
Springer Nature
Publication Date
12 2014
DOI
10.1186/2050-6511-15-48
ISSN
2050-6511