Helix–coil stability constants for amino acids in nonaqueous solvents. Studies of random poly(γ‐benzyl‐L‐glutamate‐co‐L‐alanine) and poly(γ‐benzyl‐L‐glutamate‐co‐L‐leucine) in a mixed solvent

Abstract The host–guest technique has been applied to the determination of the helix–coil stability constants of two naturally occurring amino acids, L ‐alanine and L ‐leucine, in a nonaqueous solvent system. Random copolymers containing L ‐alanine and L ‐leucine, respectively, as guest residues and γ‐benzyl‐ L ‐glutamate as the host residue were synthesized. The polymers were fractionated and characterized for their amino acid content, …