Journal article
Transactivation of the peroxisome proliferator-activated receptor is differentially modulated by hepatocyte nuclear factor-4.
Abstract
Peroxisome proliferator-activated receptors (PPARs) stimulate the expression of several genes involved in lipid metabolism by binding to specific cis-acting peroxisome proliferator-responsive elements (PPREs) via cooper-ativity with retinoid X receptors. We demonstrate here that hepatocyte nuclear factor-4 (HNF-4), another member of the nuclear hormone receptor superfamily, bound with differing affinities to the PPREs from the genes encoding …
Authors
Winrow CJ; Marcus SL; Miyata KS; Zhang B; Capone JP; Rachubinski RA
Journal
Gene Expression, Vol. 4, No. 1-2, pp. 53–62
Publication Date
1994
ISSN
1052-2166