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M34 Cardiovascular safety of nintedanib in...
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M34 Cardiovascular safety of nintedanib in subgroups by cardiovascular risk at baseline in the tomorrow and inpulsis trials

Abstract

Nintedanib is a tyrosine kinase inhibitor, a drug class that may be associated with increased risk of arterial thromboembolic events. The efficacy and safety of 52 weeks’ treatment with nintedanib versus placebo in patients with IPF were assessed in the TOMORROW and INPULSIS trials. Patients with myocardial infarction in the previous 6 months, unstable angina in the previous month, or stroke in the previous year were excluded. We assessed the …

Authors

Noth I; Wijsenbeek M; Kolb M; Bonella F; Moros L; Wachtlin D; Corte T

Volume

72

Publisher

BMJ

Publication Date

12 2017

DOI

10.1136/thoraxjnl-2017-210983.456

Name of conference

Idiopathic pulmonary fibrosis treatment update

Conference proceedings

Thorax

Issue

Suppl 3

ISSN

0040-6376