Streptozotocin induces G2 arrest in skeletal muscle myoblasts

Much of our present knowledge concerning the pathogenesis and treatment of human type 1 diabetes is due to the study of animal models of diabetes. Despite the fact that the in vivo administration of streptozotocin (STZ) has been used extensively to induce pancreatic beta‐cell death and ultimately diabetes mellitus in many animal models, little is known about the direct effects of this compound on skeletal muscle function. In the present study, …