Journal article
Breast cancer chemotherapy induces the release of cell‐free DNA, a novel procoagulant stimulus
Abstract
BACKGROUND: Thrombosis is a common complication for breast cancer patients receiving chemotherapy. However, the mechanisms by which breast cancer chemotherapeutic agents increase this risk are largely uncharacterized. Nucleic acids released by injured cells may enhance coagulation via the activation of the contact pathway.
OBJECTIVES: In this study, we examined the effects of breast cancer chemotherapy agents on the release of cell-free DNA …
Authors
SWYSTUN LL; MUKHERJEE S; LIAW PC
Journal
Journal of Thrombosis and Haemostasis, Vol. 9, No. 11, pp. 2313–2321
Publisher
Elsevier
Publication Date
11 2011
DOI
10.1111/j.1538-7836.2011.04465.x
ISSN
1538-7933