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Cholinergic nerves mediate stress-induced...

Journal article

Cholinergic nerves mediate stress-induced intestinal transport abnormalities in Wistar-Kyoto rats

Abstract

We have previously reported that acute stress alters intestinal transport physiology in Wistar-Kyoto rats, a stress-susceptible strain. In this study, we tested the hypothesis that the abnormalities in these rats are due to cholinergic mechanisms. Atropine- or saline-treated rats were exposed to acute restraint stress, and, subsequently, electrophysiological parameters of excised jejunal segments were assessed in Ussing chambers. Compared with …

Authors

Saunders PR; Hanssen NP; Perdue MH

Journal

American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 273, No. 2, pp. G486–G490

Publisher

American Physiological Society

Publication Date

August 1, 1997

DOI

10.1152/ajpgi.1997.273.2.g486

ISSN

0193-1857

Associated Experts

Mary Perdue

Professor Emeritus, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Animals Atropine Biological Transport Intestinal Mucosa Male Muscarinic Antagonists Parasympathetic Nervous System Rats Rats, Inbred WKY Rats, Wistar Reference Values Stress, Physiological

Fields of Research (FoR)

3202 Clinical sciences 3208 Medical physiology

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