Journal article
Intestinal epithelial CD23 mediates enhanced antigen transport in allergy: evidence for novel splice forms
Abstract
We previously demonstrated enhanced transepithelial antigen transport in the intestine of allergic rodents associated with elevated expression of the low-affinity IgE receptor CD23 on enterocytes. Here, we examined the role of CD23 in the transport phenomenon using CD23-/- mice and characterized the isoform of intestinal epithelial CD23. Jejunal segments of sensitized mice were challenged with antigen. Enhanced transepithelial antigen transport …
Authors
Yu LCH; Montagnac G; Yang P-C; Conrad DH; Benmerah A; Perdue MH
Journal
AJP Gastrointestinal and Liver Physiology, Vol. 285, No. 1, pp. g223–g234
Publisher
American Physiological Society
Publication Date
7 2003
DOI
10.1152/ajpgi.00445.2002
ISSN
0193-1857