Journal article
Biomarkers and the design of clinical trials in cancer
Abstract
Scientific innovation has promoted the rapid discovery and development of cancer-related biomarkers. This has fostered improved mechanistic understandings of disease biology, facilitated the development of novel targeted therapies and offers the potential to better define the natural history of a disease and to predict response to specific treatment. Clinical trials are evolving, from the use of exploratory 'correlative studies' that assist in …
Authors
Fraser GA; Meyer RM
Journal
Biomarkers in Medicine, Vol. 1, No. 3, pp. 387–397
Publisher
Taylor & Francis
Publication Date
10 2007
DOI
10.2217/17520363.1.3.387
ISSN
1752-0363