Journal article
DDE-induced changes in aromatase activity in endometrial stromal cells in culture
Abstract
Environmental toxicants are thought to play a role in several estrogen-dependent diseases including breast cancer and endometriosis. Toxicant-induced increased aromatase activity, an enzyme complex that catalyzes the final rate-limiting step in the conversion of androgens to estrogens, has been reported in assays using placental microsomes and cancer cells in vitro. These data suggest that environmental toxicants can increase aromatase activity …
Authors
Holloway AC; Stys KA; Foster WG
Journal
Endocrine, Vol. 27, No. 1, pp. 45–50
Publisher
Springer Nature
Publication Date
June 2005
DOI
10.1385/endo:27:1:045
ISSN
1355-008X