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Acid-induced fusion of liposomes: studies with...
Journal article

Acid-induced fusion of liposomes: studies with 2,3-seco-5α-cholestan-2,3-dioic acid

Abstract

The effect of 2,3-seco-5 alpha-cholestan-2,3-dioic acid on the bilayer to hexagonal phase transition temperature of dielaidoylphosphatidylethanolamine is markedly dependent on pH. Above pH 6.56, the 2,3-seco-5 alpha-cholestan-2,3-dioic acid raises the temperature of this transition, i.e., it stabilizes the bilayer phase. At pH 6.56 there is little effect of this sterol derivative on the bilayer to hexagonal phase transition temperature of …

Authors

Epand RM; Cheetham JJ; Raymer KE

Journal

Biochimica et Biophysica Acta, Vol. 940, No. 1, pp. 85–92

Publisher

Elsevier

Publication Date

5 1988

DOI

10.1016/0005-2736(88)90011-9

ISSN

0006-3002