Journal article
Acyl Chain Dependence of Diacylglycerol Activation of Protein Kinase C Activityin Vitro
Abstract
Stimulation of protein kinase C (PKC) activity in lipid vesicles in vitro was achieved by pure molecular species of diacylglycerol (DAG), specifically 1-stearoyl-2-acyl-sn-glycerol substituted with 2-arachidonoyl,2-eicosapentaenoyl or 2-docosahexaenoyl (SAG, SEG, and SDG, respectively). PKC activity was measured in lipid vesicles containing 30 mol% 1-palmitoyl-2-oleoyl-sn-glycerol-3-phospho-L-serine (POPS), 68-70 mol% …
Authors
Marignani PA; Epand RM; Sebaldt RJ
Journal
Biochemical and Biophysical Research Communications, Vol. 225, No. 2, pp. 469–473
Publisher
Elsevier
Publication Date
8 1996
DOI
10.1006/bbrc.1996.1196
ISSN
0006-291X