Journal article
fMRI functional connectivity of the periaqueductal gray in PTSD and its dissociative subtype
Abstract
BACKGROUND: Posttraumatic stress disorder (PTSD) is associated with hyperarousal and active fight or flight defensive responses. By contrast, the dissociative subtype of PTSD, characterized by depersonalization and derealization symptoms, is frequently accompanied by additional passive or submissive defensive responses associated with autonomic blunting. Here, the periaqueductal gray (PAG) plays a central role in defensive responses, where the …
Authors
Harricharan S; Rabellino D; Frewen PA; Densmore M; Théberge J; McKinnon MC; Schore AN; Lanius RA
Journal
Brain and Behavior, Vol. 6, No. 12,
Publisher
Wiley
Publication Date
December 2016
DOI
10.1002/brb3.579
ISSN
2157-9032