Journal article
Distribution of snRNPs, splicing factor SC-35 and actin in interphase nuclei: immunocytochemical evidence for differential distribution during changes in functional states
Abstract
Small nuclear ribonucleoproteins (snRNPs) play an integral role in the processing of pre-mRNA in eukaryotic nuclei. snRNPs often occur in a speckled intranuclear distribution, together with the non-snRNP splicing factor SC-35. snRNPs have also been shown to be associated with actin in the nuclear matrix, suggesting that both actin and snRNPs may be involved in the processing and transport of transcripts. The work reported here was undertaken to …
Authors
Sahlas DJ; Milankov K; Park PC; De Boni U
Journal
Journal of Cell Science, Vol. 105, No. 2, pp. 347–357
Publisher
The Company of Biologists
Publication Date
June 1, 1993
DOI
10.1242/jcs.105.2.347
ISSN
0021-9533
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
ActinsAdrenal Gland NeoplasmsAnimalsCell DifferentiationCell NucleusCells, CulturedGanglia, SpinalInterphaseMiceNerve Growth FactorsNeuronsNuclear ProteinsOrgan SpecificityPheochromocytomaRNA PrecursorsRNA SplicingRNA, NeoplasmRatsRibonucleoproteinsRibonucleoproteins, Small NuclearSerine-Arginine Splicing FactorsTumor Cells, Cultured