Chapter
Exploration of Structure-Switching in the Design of Aptamer Biosensors
Abstract
The process of “structure-switching” enables biomolecular switches to function as effective biosensing tools. Biomolecular switches can be activated or inactivated by binding to a specific target that triggers a precise conformational change in the biomolecules involved. Although many examples of aptamer-based biomolecular switches can be found in nature, substantial effort has been made in the last decade to engineer structure-switching …
Authors
Lau PS; Li Y
Book title
Biosensors Based on Aptamers and Enzymes
Series
Advances in Biochemical Engineering/Biotechnology
Volume
140
Pagination
pp. 69-92
Publisher
Springer Nature
Publication Date
2013
DOI
10.1007/10_2013_223