A General Strategy to Create RNA Aptamer Sensors Using “Regulated” Graphene Oxide Adsorption

Aptamers have been used as molecular recognition elements for sensor development in combination with graphene oxide (GO), a nanomaterial with properties including fluorescence quenching, and selective adsorption of single-stranded nucleic acids. However, previous sensor designs based on aptamer-GO adsorption have not demonstrated wide applicability, and few studies have explored the potential of RNA aptamers. Herein, we present a new sensing …