Use of flame activation of surfaces to bond PDMS to variety of substrates for fabrication of multimaterial microchannels

Silicones are widely used in industry as sealants, insulation, gaskets, coatings, seals and molds. One variety of silicone, poly dimethyl siloxane (PDMS), has been widely used for rapid prototyping of microfluidic and nanofluidic devices. The bonding of PDMS to other substrates is required to create a sealed microfluidic network. This can be achieved either by using dry bonding (e.g. oxygen plasma treatment) or wet bonding (e.g. microcontact …