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Clinical trials evaluating pathogen‐reduced...
Journal article

Clinical trials evaluating pathogen‐reduced platelet products: methodologic issues and recommendations

Abstract

BACKGROUND: Several randomized trials of platelet (PLT) products have been conducted with different study designs, endpoints, and analyses. The purpose of this article is to discuss methodologic issues in the design and analysis of PLT transfusion trials evaluating pathogen reduction technology and make recommendations for the conduct of future trials. STUDY DESIGN AND METHODS: Six randomized clinical trials of pathogen-inactivated PLT products …

Authors

Cook RJ; Heddle NM

Journal

Transfusion, Vol. 53, No. 8, pp. 1843–1855

Publisher

Wiley

Publication Date

8 2013

DOI

10.1111/j.1537-2995.2012.03951.x

ISSN

0041-1132