Journal article
Eculizumab for treatment of asthma
Abstract
INTRODUCTION: Asthma is an inflammatory disease, which can be exacerbated by stimuli such as viral infections and exposure to allergens. Asthma continues to be a profound public health problem due to asthma exacerbation in a low proportion of patients in need of more effective medications.
AREAS COVERED: The C5 complement pathway has been proposed as a new target for the treatment of asthma, supported by clinical observations of increased C5a …
Authors
Smith SG; Watson B; Clark G; Gauvreau GM
Journal
Expert Opinion on Biological Therapy, Vol. 12, No. 4, pp. 529–537
Publisher
Taylor & Francis
Publication Date
4 2012
DOI
10.1517/14712598.2012.668517
ISSN
1471-2598