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A Phase I Study of Pegylated Liposomal Doxorubicin...
Journal article

A Phase I Study of Pegylated Liposomal Doxorubicin Hydrochloride (Caelyx™) in Combination with Cyclophosphamide and Vincristine as Second-Line Treatment of Patients with Small-Cell Lung Cancer

Abstract

The purpose of this study was to determine the recommended phase II dose of liposomal doxorubicin (Caelyx ; Doxil in the United States) in combination with cyclophosphamide and vincristine for previously treated patients with good performance status with relapsed or refractory small-cell lung cancer. Twenty-one eligible patients were enrolled between November 1999 and September 2001 and received liposomal doxorubicin 25-40 mg/m2, …

Authors

Leighl NB; Burkes RL; Dancey JE; Lopez PG; Higgins BP; Walde PLD; Rudinskas LC; Rahim YH; Rodgers A; Pond GR

Journal

Clinical Lung Cancer, Vol. 5, No. 2, pp. 107–112

Publisher

Elsevier

Publication Date

9 2003

DOI

10.3816/clc.2003.n.024

ISSN

1525-7304