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Expression of EGFR, HER-2/neu and KIT in germ cell...
Journal article

Expression of EGFR, HER-2/neu and KIT in germ cell tumours

Abstract

BackgroundGerm cell tumours (GCTs) represent an extraordinarily chemosensitive malignancy. However, 20–30% of patients with advanced disease cannot be cured by currently available treatments. The role of tyrosine kinase receptors has been widely studied in other malignancies. Yet, limited information is available on GCTs.MethodsOne hundred and nine paraffin-embedded GCTs in 84 patients were assessed by immunohistochemistry for epidermal growth …

Authors

Durán I; García-Velasco A; Ballestín C; García E; Martínez-Tello F; Pond GR; García-Carbonero R; Cortés-Funés H; Paz-Ares L

Journal

Clinical and Translational Oncology, Vol. 12, No. 6, pp. 443–449

Publisher

Springer Nature

Publication Date

6 2010

DOI

10.1007/s12094-010-0532-6

ISSN

1699-048X