Journal article
Trends in the application of dynamic allocation methods in multi-arm cancer clinical trials
Abstract
BACKGROUND: Dynamic allocation (DA) methods which attempt to balance baseline prognostic factors between treatment arms, can be used in multi-arm clinical trials to sequentially allocate patients to treatment. Although some experts express concern regarding the validity of inference from trials using DA, others believe DA methods produce more credible results.
PURPOSE: A review of published multi-arm cancer clinical trials was conducted to …
Authors
Pond GR; Tang PA; Welch SA; Chen EX
Journal
Clinical Trials, Vol. 7, No. 3, pp. 227–234
Publisher
SAGE Publications
Publication Date
6 2010
DOI
10.1177/1740774510368301
ISSN
1740-7745