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Unfavourable effects of medically indicated oral...
Journal article

Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis

Abstract

Procoagulant and antifibrinolytic activity has been associated with idiopathic pulmonary fibrosis (IPF); however, investigation of anticoagulant therapy in IPF has suggested deleterious effects. This post hoc analysis evaluated the effect of medically indicated anticoagulation on mortality and other clinical outcomes in IPF.Patients randomised to placebo (n=624) from three controlled trials in IPF were analysed by oral anticoagulant use. …

Authors

Kreuter M; Wijsenbeek MS; Vasakova M; Spagnolo P; Kolb M; Costabel U; Weycker D; Kirchgaessler K-U; Maher TM

Journal

European Respiratory Journal, Vol. 47, No. 6, pp. 1776–1784

Publisher

European Respiratory Society (ERS)

Publication Date

6 2016

DOI

10.1183/13993003.02087-2015

ISSN

0903-1936