Journal article
Induction of interleukin‐1/and interleukin‐8 mRNAs and proteins by TGFβ1 in rat lung alveolar epithelial cells
Abstract
The transforming growth factor-beta (TGF-beta) has been shown to increase in lung injury and in fibrotic states of the lung. In the current study, we sought to investigate whether TGF beta 1 induced the expression of IL-1 alpha and IL-8 in rat alveolar epithelial cells. We evaluated TGF beta 1, IL-1 alpha, and IL-8 expression by immunofluorescence in silica-injured and saline-treated control rat lungs. Antibodies to IL-1 alpha, IL-8, and TGF …
Authors
Kumar NM; Rabadi NH; Sigurdson LS; Schünemann HJ; Lwebuga‐Mukasa JS
Journal
Journal of Cellular Physiology, Vol. 169, No. 1, pp. 186–199
Publisher
Wiley
Publication Date
October 1996
DOI
10.1002/(sici)1097-4652(199610)169:1<186::aid-jcp19>3.0.co;2-b
ISSN
0021-9541