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Journal article

Cellular magnetic resonance imaging of monocyte-derived dendritic cell migration from healthy donors and cancer patients as assessed in a scid mouse model

Abstract

BACKGROUND AIMS. The use of dendritic cells (DC) as an adjuvant in cell-based immunotherapeutic cancer vaccines is a growing field of interest. A reliable and non-invasive method to track the fate of autologous DC following their administration to patients is required in order to confirm that clinically sufficient numbers are reaching the lymph node (LN). We demonstrate that an immunocompromised mouse model can be used to conduct translational …

Authors

Zhang X; de Chickera SN; Willert C; Economopoulos V; Noad J; Rohani R; Wang AY; Levings MK; Scheid E; Foley R

Journal

Cytotherapy, Vol. 13, No. 10, pp. 1234–1248

Publisher

Elsevier

Publication Date

11 2011

DOI

10.3109/14653249.2011.605349

ISSN

1465-3249