Journal article
Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes
Abstract
Aims/hypothesisA comprehensive assessment of skeletal muscle ultrastructure and mitochondrial bioenergetics has not been undertaken in individuals with type 1 diabetes. This study aimed to systematically assess skeletal muscle mitochondrial phenotype in young adults with type 1 diabetes.MethodsPhysically active, young adults (men and women) with type 1 diabetes (HbA1c 63.0 ± 16.0 mmol/mol [7.9% ± 1.5%]) and without type 1 diabetes (control), …
Authors
Monaco CMF; Hughes MC; Ramos SV; Varah NE; Lamberz C; Rahman FA; McGlory C; Tarnopolsky MA; Krause MP; Laham R
Journal
Diabetologia, Vol. 61, No. 6, pp. 1411–1423
Publisher
Springer Nature
Publication Date
June 2018
DOI
10.1007/s00125-018-4602-6
ISSN
0012-186X