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Characteristics of [3H] propyl...
Journal article

Characteristics of [3H] propyl beta-carboline-3-carboxylate binding to benzodiazepine receptors in human brain.

Abstract

Characterization of the binding of derivatives of beta-carboline-3-carboxylate, a putative endogenous ligand for benzodiazepine (BZ) receptors, has not previously been attempted in normal human brain. In the present study, we demonstrated saturable, high affinity binding of [3H] propyl beta-carboline-3-carboxylate [3H] PrCC) in normal human frontal cerebral cortex and cerebellum exhibiting pharmacological specificity similar to [3H] diazepam …

Authors

Chiu P; Chiu S; Mishra RK

Journal

Research Communications in Molecular Pathology and Pharmacology, Vol. 44, No. 2, pp. 199–213

Publication Date

May 1984

ISSN

1078-0297