Journal article
The Gas-Phase Dipeptide Analogue Acetyl-phenylalanyl-amide: A Model for the Study of Side Chain/Backbone Interactions in Proteins
Abstract
The issue of the influence of the side chain/backbone interaction on the local conformational preferences of a phenylalanine residue in a peptide chain is addressed. A synergetic approach is used, which combines gas-phase UV spectroscopy as well as gas-phase IR/UV double-resonance experiments with DFT and post Hartree-Fock calculations. N-Acetyl-Phe-amide was chosen as a model system for which three different conformers were observed. The most …
Authors
Chin W; Mons M; Dognon J-P; Mirasol R; Chass G; Dimicoli I; Piuzzi F; Butz P; Tardivel B; Compagnon I
Journal
The Journal of Physical Chemistry A, Vol. 109, No. 24, pp. 5281–5288
Publisher
American Chemical Society (ACS)
Publication Date
June 1, 2005
DOI
10.1021/jp048037j
ISSN
1089-5639