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Placebo-controlled trials in pediatric urology: A...
Journal article

Placebo-controlled trials in pediatric urology: A cautionary view from an ethical perspective

Abstract

The ethical dispute regarding placebo-controlled trials is discussed in this review. Important issues, such as clinical equipoise, fiduciary obligation and middle ground theory, are examined in the context of pediatric urology clinical research. After reviewing the literature, the authors summarize specific indications for placebo-controlled trials in pediatric urology, and emphasize that physicians have ethical and moral obligations to …

Authors

Braga LHP; Bagli DJ; Lorenzo AJ

Journal

Journal of Pediatric Urology, Vol. 6, No. 5, pp. 435–442

Publisher

Elsevier

Publication Date

October 2010

DOI

10.1016/j.jpurol.2010.02.208

ISSN

1477-5131