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Clinical Use of Creatine in Neuromuscular and...
Journal article

Clinical Use of Creatine in Neuromuscular and Neurometabolic Disorders

Abstract

Many of the neuromuscular (e.g., muscular dystrophy) and neurometabolic (e.g., mitochondrial cytopathies) disorders share similar final common pathways of cellular dysfunction that may be favorably influenced by creatine monohydrate (CrM) supplementation. Studies using the mdx model of Duchenne muscular dystrophy have found evidence of enhanced mitochondrial function, reduced intra-cellular calcium and improved performance with CrM …

Authors

Tarnopolsky MA

Journal

Subcellular Biochemistry, Vol. 46, , pp. 183–204

Publisher

Springer Nature

Publication Date

2007

DOI

10.1007/978-1-4020-6486-9_10

ISSN

0306-0225