Journal article
Effect of Rosuvastatin on Carotid Intima-Media Thickness in Children With Heterozygous Familial Hypercholesterolemia
Abstract
BACKGROUND: Heterozygous familial hypercholesterolemia (HeFH) is an autosomal dominant disorder leading to premature atherosclerosis. Children with HeFH exhibit early signs of atherosclerosis manifested by increased carotid intima-media thickness (IMT). In this study, we assessed the effect of 2-year treatment with rosuvastatin on carotid IMT in children with HeFH.
METHODS: Children with HeFH (age, 6-<18 years) and low-density lipoprotein …
Authors
Braamskamp MJAM; Langslet G; McCrindle BW; Cassiman D; Francis GA; Gagne C; Gaudet D; Morrison KM; Wiegman A; Turner T
Journal
Circulation, Vol. 136, No. 4, pp. 359–366
Publisher
Wolters Kluwer
Publication Date
July 25, 2017
DOI
10.1161/circulationaha.116.025158
ISSN
0009-7322