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Transcriptional profiling of primary endometrial...
Journal article

Transcriptional profiling of primary endometrial epithelial cells following acute HIV‐1 exposure reveals gene signatures related to innate immunity

Abstract

PROBLEM: Genital epithelial cells (GECs) line the mucosal surface of the female genital tract (FGT) and are the first cells that interface with both commensal microbiota and sexually transmitted pathogens. Despite the protective barrier formed by GECs, the FGT is a major site of HIV-1 infection. This highlights the importance of studying the interaction of HIV-1 and GECs. METHOD OF STUDY: Using microarray analysis, we characterized the …

Authors

Zahoor MA; Woods MW; Dizzell S; Nazli A; Mueller KM; Nguyen PV; Verschoor CP; Kaushic C

Journal

American Journal Of Reproductive Immunology, Vol. 79, No. 4,

Publisher

Wiley

Publication Date

April 2018

DOI

10.1111/aji.12822

ISSN

1046-7408