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Rat model of cancer-induced bone pain
Journal article

Rat model of cancer-induced bone pain

Abstract

INTRODUCTION: Clinical data on cancer-induced bone pain (CIBP) suggest extensive changes in sensory function. In a previous investigation of an animal model of CIBP, we have observed that changes in intrinsic membrane properties and excitability of dorsal root ganglion (DRG) nociceptive neurons correspond to mechanical allodynia and hyperalgesia. OBJECTIVES: To investigate the mechanisms underlying changes in nonnociceptive sensory neurons in …

Authors

Zhu YF; Ungard R; Zacal N; Huizinga JD; Henry JL; Singh G

Journal

PAIN Reports, Vol. 2, No. 4,

Publisher

Wolters Kluwer

Publication Date

7 2017

DOI

10.1097/pr9.0000000000000603

ISSN

2471-2531