Journal article
The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis
Abstract
The clinical practice of hyperthermic intraperitoneal chemoperfusion (HIPEC) for carcinomatosis has lacked preclinical justification. A standardized mouse model was created to evaluate the independent effects of intraperitoneal chemotherapy. Diffuse colorectal carcinomatosis was generated in mice prior to intraperitoneal lavage with mitomycin C (MMC) at clinically comparable dosing for variable lengths of time. Tumor volumes, MMC tissue …
Authors
FRANCESCUTTI V; RIVERA L; SESHADRI M; KIM M; HASLINGER M; CAMORIANO M; ATTWOOD K; KANE JM; SKITZKI JJ
Journal
Oncology Reports, Vol. 30, No. 1, pp. 35–42
Publisher
Spandidos Publications
Publication Date
7 2013
DOI
10.3892/or.2013.2473
ISSN
1021-335X