Journal article
A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties
Abstract
Organometallic compounds bearing the redox motif [ferrocenyl-ene-phenol] have very promising antiproliferative properties which have been further improved by incorporating pertinent substituents able to engender new mechanisms. Here we show that novel ferrociphenols bearing a hydroxypropyl chain exhibit strong antiproliferative effects, in most cases much better than those of cisplatin, tamoxifen, or of previously described ferrociphenols …
Authors
Wang Y; Dansette PM; Pigeon P; Top S; McGlinchey MJ; Mansuy D; Jaouen G
Journal
Chemical Science, Vol. 9, No. 1, pp. 70–78
Publisher
Royal Society of Chemistry (RSC)
Publication Date
2018
DOI
10.1039/c7sc04213b
ISSN
2041-6520