Photoluminescence model for a hybrid aptamer-GaAs optical biosensor

The present work describes the development of a hybrid GaAs-aptamers biosensor for the label-free detection of adenosine 5′-triphosphate (ATP). The implemented sensing strategy relies on the sensitivity of the GaAs photoluminescence (PL) emission to the local environment at its surface. Specifically, GaAs substrates were chemically modified with thiol-derivatized oligonucleotide aptamers following conventional condensed-phase deposition …