Journal article
Temporal fractal analysis of the rs-BOLD signal identifies brain abnormalities in autism spectrum disorder
Abstract
BACKGROUND: Brain connectivity in autism spectrum disorders (ASD) has proven difficult to characterize due to the heterogeneous nature of the spectrum. Connectivity in the brain occurs in a complex, multilevel and multi-temporal manner, driving the fluctuations observed in local oxygen demand. These fluctuations can be characterized as fractals, as they auto-correlate at different time scales. In this study, we propose a model-free complexity …
Authors
Dona O; Hall GB; Noseworthy MD
Journal
PLOS ONE, Vol. 12, No. 12,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0190081
ISSN
1932-6203