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Efficacy and safety of stress ulcer prophylaxis in...
Journal article

Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials

Abstract

PurposeStress ulcer prophylaxis (SUP) is commonly prescribed in the intensive care unit. However, data from systematic reviews and conventional meta-analyses are limited by imprecision and restricted to direct comparisons. We conducted a network meta-analysis of randomized clinical trials (RCTs) to examine the safety and efficacy of drugs available for SUP in critically ill patients.MethodsWe searched MEDLINE, EMBASE, and the Cochrane Library …

Authors

Alhazzani W; Alshamsi F; Belley-Cote E; Heels-Ansdell D; Brignardello-Petersen R; Alquraini M; Perner A; Møller MH; Krag M; Almenawer S

Journal

Intensive Care Medicine, Vol. 44, No. 1, pp. 1–11

Publisher

Springer Nature

Publication Date

January 2018

DOI

10.1007/s00134-017-5005-8

ISSN

0342-4642