Journal article
Maraba virus-vectored cancer vaccines represent a safe and novel therapeutic option for cats
Abstract
Direct killing of malignant cells combined with induction of tumour-specific immune responses makes oncolytic vaccines attractive for cancer therapy. We previously developed a heterologous cancer immunization strategy that utilized a replication-defective adenovirus-vectored primary vaccine encoding a tumour antigen followed by boosting with a replication-competent Maraba virus expressing the same antigen. To assess the safety of oncolytic …
Authors
Hummel J; Bienzle D; Morrison A; Cieplak M; Stephenson K; DeLay J; Woods JP; Lichty BD; Bridle BW
Journal
Scientific Reports, Vol. 7, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-017-15992-4
ISSN
2045-2322