Journal article
Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children
Abstract
BACKGROUND: We have shown that intrauterine growth restriction (IUGR) leads to increased preference for palatable foods at different ages in both humans and rodents. In IUGR rodents, altered striatal dopamine signaling associates with a preference for palatable foods.
OBJECTIVES: Our aim was to investigate if a multilocus genetic score reflecting dopamine-signaling capacity is differently associated with spontaneous palatable food intake in …
Authors
Silveira PP; Pokhvisneva I; Gaudreau H; Atkinson L; Fleming AS; Sokolowski MB; Steiner M; Kennedy JL; Dubé L; Levitan RD
Journal
Appetite, Vol. 120, , pp. 596–601
Publisher
Elsevier
Publication Date
January 2018
DOI
10.1016/j.appet.2017.10.021
ISSN
0195-6663
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AllelesBirth WeightBody Mass IndexCanadaChild, PreschoolDietDietary SugarsDopamineDopamine Plasma Membrane Transport ProteinsFemaleFetal DevelopmentFetal Growth RetardationFood PreferencesGenotyping TechniquesHumansMaleMultilocus Sequence TypingPediatric ObesityPolymorphism, GeneticReceptors, Dopamine D2Receptors, Dopamine D4Signal TransductionSnacks