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Collagen platelet receptor polymorphisms integrin...
Journal article

Collagen platelet receptor polymorphisms integrin α2β1 C807T and GPVI Q317L and risk of ischemic stroke

Abstract

Several polymorphisms of integrin alpha2beta1 and glycoprotein (GP) VI that may modify platelet-collagen interactions or subsequent signaling have been described. We conducted a case-control study involving 180 stroke patients and 172 controls to determine whether the alpha2 C807T and GPVI Q317L polymorphisms were associated with an increased risk of ischemic stroke. We found no statistically significant differences in the distribution of …

Authors

Cole VJ; Staton JM; Eikelboom JW; Hankey GJ; Yi Q; Shen Y; Berndt MC; Baker RI

Journal

Journal of Thrombosis and Haemostasis, Vol. 1, No. 5, pp. 963–970

Publisher

Elsevier

Publication Date

May 2003

DOI

10.1046/j.1538-7836.2003.00179.x

ISSN

1538-7933